分子量(DA)
Molecular Weight
Calculated MW: 38 kDa; Observed MW: 74 kDa
免疫原
Recombinant protein of human CD86 (NP_787058.4).
稀释比例
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
背景(Background)
Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.
其他名称
CD86; CD28LG2; T-lymphocyte activation antigen CD86; Activation B7-2 antigen; B70; BU63; CTLA-4 counter-receptor B7.2; FUN-1; CD antigen CD86
人基因ID
SwissProt ID
P42081
储存(Storage)
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.