免疫原
The antiserum was produced against synthesized peptide derived from human HCC1. AA range:147-196
特异性
CIP29 Polyclonal Antibody detects endogenous levels of CIP29 protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene encodes a protein that is upregulated in response to various cytokines. The encoded protein may play a role in cell cycle progression. A translocation between this gene and the myeloid/lymphoid leukemia gene, resulting in expression of a chimeric protein, has been associated with acute myelomonocytic leukemia. Pseudogenes exist on chromosomes 7 and 8. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009],
功能
transcription, regulation of transcription, DNA-dependent, regulation of translation, posttranscriptional regulation of gene expression, regulation of cellular protein metabolic process, regulation of transcription, regulation of RNA metabolic process,
蛋白名称
SAP domain-containing ribonucleoprotein
其他名称
SARNP; HCC1; HSPC316; SAP domain-containing ribonucleoprotein; Cytokine-induced protein of 29 kDa; Nuclear protein Hcc-1; Proliferation-associated cytokine-inducible protein CIP29
细胞定位
Nucleus. Nucleus speckle.
组织表达
Low expression in spleen, liver, pancreas, testis, thymus, heart, and kidney. Increased levels are seen in hepatocellular carcinoma and pancreatic adenocarcinoma.
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