分子量(DA)
Molecular Weight
Calculated MW: 16 kDa; Observed MW: 12 kDa
免疫原
A synthesized peptide derived from human HBG1/2
背景(Background)
The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008],
基因名称(Gene Name)
HBG1/HBG2
简称
Gamma 1 globin;Gamma 2 globin;Gamma A hemoglobin; Gamma globin; Hb FAgamma; Hb F Ggamma; HBG1; HBG2:HBGA: HBGR
人基因ID
SwissProt ID
P69891/P69892
人蛋白质序列数据库
Gene ID
3047/3048
储存(Storage)
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.