免疫原
Synthesized peptide derived from human GARNL1 (Phospho-T736)
特异性
This antibody detects endogenous phospho levels of GARNL1 (Phospho-T736) at Human, Mouse, Rat
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC-p 1:50-200, WB 1:500-2000. IF 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
This gene encodes a major subunit of the RAL-GTPase activating protein. A similar protein in mouse binds E12, a transcriptional regulator of immunoglobulin genes. The mouse protein also functions in skeletal muscle by binding to the regulatory 14-3-3 proteins upon stimulation with insulin or muscle contraction. A pseudogene of this gene has been identified on chromosome 9. [provided by RefSeq, Oct 2016],
功能
regulation of small GTPase mediated signal transduction,
基因名称(Gene Name)
RALGAPA1 GARNL1 KIAA0884 TULIP1
蛋白名称
GARNL1 (Phospho-T736)
其他名称
Ral GTPase-activating protein subunit alpha-1 (GAP-related-interacting partner to E12;GRIPE;GTPase-activating Rap/Ran-GAP domain-like 1;Tuberin-like protein 1;p240)
Fields
>>Ras signaling pathway
细胞定位
Cytoplasm . Nucleus . Translocated to the nucleus, when associated with TCF3/E12. .