免疫原
The antiserum was produced against synthesized peptide derived from the C-terminal region of human OGN. AA range:231-280
特异性
Osteoglycin Polyclonal Antibody detects endogenous levels of Osteoglycin protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded protein induces ectopic bone formation in conjunction with transforming growth factor beta and may regulate osteoblast differentiation. High expression of the encoded protein may be associated with elevated heart left ventricular mass. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],
功能
function:Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2.,similarity:Belongs to the small leucine-rich proteoglycan (SLRP) family. Class III subfamily.,similarity:Contains 7 LRR (leucine-rich) repeats.,tissue specificity:Bone.,
其他名称
OGN; OIF; SLRR3A; Mimecan; Osteoglycin; Osteoinductive factor; OIF
细胞定位
Secreted, extracellular space, extracellular matrix .
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