功能
PTM:Sumoylated.,sequence caution:Contaminating sequence. Potential poly-A sequence.,sequence caution:Translation N-terminally extended.,similarity:Contains 1 PWI domain.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subcellular location:Detected predominantly in nuclear speckles. Cytoplasmic localization is faint.,subunit:Interacts with SRRM1. Specifically associates with functional splicing complexes, including Sm proteins and U1, U2, U4, U5 and U6 snRNAs. Associates with exon junction complex (EJC) proteins, including APEX1, BAT1, NCBP1, RBM8A and RNPS1. Interaction with NCBP1 is RNA-dependent.,
细胞定位
Nucleus speckle. Cytoplasm. Colocalizes predominantly, with SFRS2 and LUC7L3 splicing factors, in nuclear speckles. Cytoplasmic localization is faint.
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