免疫原
Synthesized peptide derived from human GRCR1 AA range: 132-182
特异性
This antibody detects endogenous levels of GRCR1 at Human/Mouse
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
This gene is one of 60 loci associated with autosomal-recessive nonsyndromic hearing impairment. This gene encodes a protein which contains GRX-like domains; these domains play a role in the S-glutathionylation of proteins and may be involved in actin organization in hair cells. [provided by RefSeq, Sep 2010],
功能
similarity:Belongs to the GRXCR1 family.,similarity:Contains 1 glutaredoxin domain.,
基因名称(Gene Name)
GRXCR1 DFNB25
细胞定位
Cell projection, stereocilium . Cell projection, microvillus . Cell projection, kinocilium . In the inner ear, localized to stereocilia, apical microvilli of sensory cells and kinocilia. .
组织表达
Expressed at low levels in adult lung, brain and duodenum with moderate levels in testis. Highly expressed in fetal cochlea.