免疫原
Synthesized peptide derived from human SNX17 AA range: 398-448
特异性
This antibody detects endogenous levels of SNX17 at Human/Mouse/Rat
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000;IHC-p 1:50-300
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景（Background）
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a B41 domain. This protein interacts with the cytoplasmic domain of P-selectin, and may function in the intracellular trafficking of P-selectin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2012],
功能
domain:The PX domain is required for association with endosomes.,function:May be involved in protein trafficking.,similarity:Belongs to the sorting nexin family.,similarity:Contains 1 PX (phox homology) domain.,similarity:Contains 1 Ras-associating domain.,subcellular location:Associated with early endosomes.,subunit:Interacts with the C-termini of P-selectin, PTC, LDLR, VLDLR, LRP1 and LRP8.,
基因名称（Gene Name）
SNX17 KIAA0064
细胞定位
Cytoplasm . Early endosome . Cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side .
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