免疫原
Synthesized peptide derived from NOP56 at AA range: 191-240
特异性
NOP56 Polyclonal Antibody detects endogenous levels of NOP56
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000.. IF 1:50-200
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
Nop56p is a yeast nucleolar protein that is part of a complex with the nucleolar proteins Nop58p and fibrillarin. Nop56p is required for assembly of the 60S ribosomal subunit and is involved in pre-rRNA processing. The protein encoded by this gene is similar in sequence to Nop56p and is also found in the nucleolus. Expansion of a GGCCTG repeat from 3-8 copies to 1500-2500 copies in an intron of this gene results in spinocerebellar ataxia 36. Multiple transcript variants encoding several different isoforms have been found for this gene, but the full-length nature of most of them has not been determined. [provided by RefSeq, Jul 2016],
功能
function:Required for 60S ribosomal subunit biogenesis.,similarity:Belongs to the NOP5/NOP56 family.,similarity:Contains 1 Nop domain.,subunit:Interacts with NOP1 and NOP58.,
其他名称
Nucleolar protein 56 (Nucleolar protein 5A)
Fields
>>Ribosome biogenesis in eukaryotes;>>Spinocerebellar ataxia
细胞定位
Nucleus, nucleolus . Cytoplasm . Nucleus, nucleoplasm .
组织表达
Brain,Cervix carcinoma,Epithelium,Uterus,
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