免疫原
Synthesized peptide derived from human TM138 AA range: 75-125
特异性
This antibody detects endogenous levels of TM138 at Human/Mouse/Rat
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
This gene encodes a multi-pass transmembrane protein. Reduced expression of this gene in mouse fibroblasts causes short cilia and failure of ciliogenesis. Expression of this gene is tightly coordinated with expression of the neighboring gene TMEM216. Mutations in this gene are associated with the autosomal recessive neurodevelopmental disorder Joubert Syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012],
功能
similarity:Belongs to the TMEM138 family.,
基因名称(Gene Name)
TMEM138 HSPC196 HSPC198
细胞定位
Vacuole membrane ; Multi-pass membrane protein . Cell projection, cilium . Localizes to vesicles en route to the base of cilium.