免疫原
Synthesized peptide derived from human ENW1 AA range: 442-492
特异性
This antibody detects endogenous levels of human ENW1
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
基因名称(Gene Name)
ERVW-1 ERVWE1
蛋白名称
HERV-W_7q21.2 provirus ancestral Env polyprotein (Endogenous retrovirus group W member 1) (Env-W) (Envelope polyprotein gPr73) (Enverin) (HERV-7q Envelope protein) (HERV-W envelope protein) (Syncytin)
细胞定位
[Surface protein]: Cell membrane ; Peripheral membrane protein . The surface protein is not anchored to the membrane, but localizes to the extracellular surface through its binding to TM. .; [Transmembrane protein]: Cell membrane ; Single-pass type I membrane protein .; [Syncytin-1]: Virion .
组织表达
Expressed at higher level in placental syncytiotrophoblast. Expressed at intermediate level in testis. Seems also to be found at low level in adrenal tissue, bone marrow, breast, colon, kidney, ovary, prostate, skin, spleen, thymus, thyroid, brain and trachea. Both mRNA and protein levels are significantly increased in the brain of individuals with multiple sclerosis, particularly in astrocytes and microglia.