免疫原
Synthetic peptide from human protein at AA range: 1-50
特异性
The antibody detects endogenous TMPO protein
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000, ELISA 1:10000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
The protein encoded by TMPO (thymopoietin) resides in the nucleus and may play a role in the assembly of the nuclear lamina, and thus help maintain the structural organization of the nuclear envelope. It may function as a receptor for the attachment of lamin filaments to the inner nuclear membrane. Mutations in TMPO are associated with dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for TMPO.
功能
regulation of transcription,
基因名称(Gene Name)
TMPO LAP2
细胞定位
Nucleus. Chromosome. Expressed diffusely throughout the nucleus.
组织表达
Expressed in many tissues. Most abundant in adult thymus and fetal liver.