免疫原
Synthesized peptide derived from human ABT1 AA range: 140-190
特异性
This antibody detects endogenous levels of ABT1 at Human/Mouse/Rat
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
Basal transcription of genes by RNA polymerase II requires the interaction of TATA-binding protein (TBP) with the core region of class II promoters. Studies in mouse suggest that the protein encoded by this gene likely activates basal transcription from class II promoters by interaction with TBP and the class II promoter DNA. [provided by RefSeq, Jul 2008],
功能
function:Could be a novel TATA-binding protein (TBP) which can function as a basal transcription activator. Can act as a regulator of basal transcription for class II genes.,similarity:Belongs to the ESF2/ABP1 family.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:Interacts with ESF1/ABTAP.,
细胞定位
Nucleus . Nucleus, nucleolus .