免疫原
Synthesized peptide derived from human ESX1 AA range: 327-377
特异性
This antibody detects endogenous levels of ESX1 at Human
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景（Background）
This gene encodes a dual-function 65 kDa protein that undergoes proteolytic cleavage to produce a 45 kDa N-terminal fragment with a paired-like homeodomain and a 20 kDa C-terminal fragment with a proline-rich domain. The C-terminal fragment localizes to the cytoplasm while the N-terminal fragment localizes exclusively to the nucleus. In contrast to human, the mouse homolog has a novel PN/PF motif in the C-terminus and is paternally imprinted in placental tissue. This gene likely plays a role in placental development and spermatogenesis. [provided by RefSeq, Jan 2010],
功能
similarity:Contains 1 homeobox DNA-binding domain.,tissue specificity:Expressed in placenta and testis.,
基因名称（Gene Name）
ESX1 ESX1L ESX1R
Fields
>>Signaling pathways regulating pluripotency of stem cells
细胞定位
Cytoplasm . Nucleus . ESXR1-N localizes specifically to the nucleus while ESXR1-C localizes specifically to the cytoplasm.
组织表达
Expressed in placenta and testis. Expressed in testicular germ cell tumors.
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