免疫原
Synthetic Peptide of Histone H1 (Tri Methyl Lys25)
特异性
The antibody detects endogenous Histone H1 (Tri Methyl Lys25) protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen.
背景（Background）
Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015],
功能
function:Histones H1 are necessary for the condensation of nucleosome chains into higher order structures.,similarity:Belongs to the histone H1/H5 family.,
基因名称（Gene Name）
HIST1H1A/HIST1H1C/HIST1H1D/HIST1H1E
蛋白名称
Histone H1.1/Histone H1.2/Histone H1.3/Histone H1.4
其他名称
H1K25ME3; HIST1H1A; H1F1; Histone H1.1; Histone H1a; HIST1H1C; H1F2; Histone H1.2; Histone H1c; Histone H1d; Histone H1s-1; HIST1H1D; H1F3; Histone H1.3; Histone H1c; Histone H1s-2; HIST1H1E; H1F4; Histone H1.4; Histone H1b; Histone H1s-4
人基因ID
3024/3006/3007/3008
人蛋白质序列数据库
Q02539/P16403/P16402/P10412
小鼠基因ID
80838/50708/14957/50709
细胞定位
Nucleus . Chromosome . Mainly localizes in euchromatin.
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