免疫原
Synthesized peptide derived from human protein . at AA range: 260-340
特异性
DNJB2 Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene is almost exclusively expressed in the brain, mainly in the neuronal layers. It encodes a protein that shows sequence similarity to bacterial DnaJ protein and the yeast homologs. In bacteria, this protein is implicated in protein folding and protein complex dissociation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2011],
功能
alternative products:Experimental confirmation may be lacking for some isoforms,similarity:Contains 1 J domain.,similarity:Contains 2 UIM (ubiquitin-interacting motif) repeats.,tissue specificity:Brain (neuronal layers). Weakly, in skeletal muscle and spleen.,
基因名称（Gene Name）
DNAJB2 HSJ1 HSPF3
蛋白名称
DnaJ homolog subfamily B member 2 (DnaJ protein homolog 1) (Heat shock 40 kDa protein 3) (Heat shock protein J1) (HSJ-1)
Fields
>>Protein processing in endoplasmic reticulum
细胞定位
[Isoform 2]: Cytoplasm . Nucleus .; [Isoform 1]: Endoplasmic reticulum membrane ; Lipid-anchor ; Cytoplasmic side .
组织表达
More abundantly expressed in neocortex, cerebellum, spinal cord and retina where it is expressed by neuronal cells (at protein level) (PubMed:1599432, PubMed:12754272). Detected at much lower level in non-neuronal tissues including kidney, lung, heart, skeletal muscle, spleen and testis (at protein level) (PubMed:12754272, PubMed:1599432). Isoform 1 is more abundant in neocortex and cerebellum compared to isoform 2 (at protein level) (PubMed:12754272).
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