免疫原
The antiserum was produced against synthesized peptide derived from human SUCNR1. AA range:100-149
特异性
GPR91 Polyclonal Antibody detects endogenous levels of GPR91 protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This gene encodes a G-protein-coupled receptor for succinate, an intermediate molecule of the citric acid cycle. It is involved in the promotion of hematopoietic progenitor cell development, and it has a potential role in renovascular hypertension which has known correlations to renal failure, diabetes and atherosclerosis. [provided by RefSeq, Oct 2009],
功能
function:Receptor for succinate.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed specifically in kidney.,
蛋白名称
Succinate receptor 1
其他名称
SUCNR1; GPR91; Succinate receptor 1; G-protein coupled receptor 91; P2Y purinoceptor 1-like
Fields
>>cAMP signaling pathway
细胞定位
Cell membrane ; Multi-pass membrane protein .
组织表达
Expressed specifically in kidney.