免疫原
Synthesized peptide derived from human protein . at AA range: 140-220
特异性
RND2 Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene encodes a member of the Rho GTPase family, whose members play a key role in the regulation of actin cytoskeleton organization in response to extracellular growth factors. This particular family member has been implicated in the regulation of neuronal morphology and endosomal trafficking. The gene localizes to chromosome 17 and is the centromeric neighbor of the breast-ovarian cancer susceptibility gene BRCA1. [provided by RefSeq, Jul 2008],
功能
function:May be specifically involved in neuronal and hepatic functions. Is a C3 toxin-insensitive member of the Rho subfamily.,similarity:Belongs to the small GTPase superfamily. Rho family.,subcellular location:Colocalizes with RACGAP1 in Golgi-derived proacrosomal vesicles and the acrosome.,subunit:Interacts with the Rho-GAP domain of RACGAP1. Interacts with UBXD5.,tissue specificity:Highly expressed in testis.,
基因名称（Gene Name）
RND2 ARHN RHO7
蛋白名称
Rho-related GTP-binding protein RhoN (Rho family GTPase 2) (Rho-related GTP-binding protein Rho7) (Rnd2)
细胞定位
Cytoplasmic vesicle, secretory vesicle, acrosome membrane ; Lipid-anchor ; Cytoplasmic side . Colocalizes with RACGAP1 in Golgi-derived proacrosomal vesicles and the acrosome. .
组织表达
Highly expressed in testis.
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