免疫原
Synthesized peptide derived from human MIDN
特异性
This antibody detects endogenous levels of MIDN at Human, Mouse
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Facilitates ubiquitin-independent proteasomal degradation of polycomb protein CBX4. Plays a role in inhibiting the activity of glucokinase GCK and both glucose-induced and basal insulin secretion.
蛋白名称
Midnolin (Midbrain nucleolar protein)
细胞定位
Nucleus, nucleolus . Nucleus . Cytoplasm, cytosol . Detected in the nucleus and nucleolus with no expression in the cytoplasm (By similarity). However, a later study finds expression in the nucleus and cytoplasm with no expression in the nucleolus (PubMed:24187134). .
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)