免疫原
The antiserum was produced against synthesized peptide derived from human B3GALT1. AA range:61-110
特异性
β-1,3-Gal-T1 Polyclonal Antibody detects endogenous levels of β-1,3-Gal-T1 protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3
功能
cofactor:Manganese.,function:Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-N-acetylglucosamine (beta-GlcNAc) residue. Involved in the biosynthesis of the carbohydrate moieties of glycolipids and glycoproteins. Inactive towards substrates with terminal alpha-N-acetylglucosamine (alpha-GlcNAc) or alpha-N-acetylgalactosamine (alpha-GalNAc) residues.,online information:Beta-1,3-galactosyltransferase 1,online information:GlycoGene database,pathway:Protein modification; protein glycosylation.,similarity:Belongs to the glycosyltransferase 31 family.,tissue specificity:Detected in brain and colon mucosa and to a lesser extent in colon adenocarcinoma cells.,
蛋白名称
Beta-1,3-galactosyltransferase 1
其他名称
B3GALT1; Beta-1; 3-galactosyltransferase 1; Beta-1,3-GalTase 1; Beta3Gal-T1; Beta3GalT1; UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1
Fields
>>Glycosphingolipid biosynthesis - lacto and neolacto series;>>Metabolic pathways
细胞定位
Golgi apparatus membrane ; Single-pass type II membrane protein .
组织表达
Detected in brain and colon mucosa and to a lesser extent in colon adenocarcinoma cells.
联系我们
关注我们
您当前的位置： 
说明书
成功添加到购物车
