免疫原
Synthesized peptide derived from human IL-17 AA range: 50-100
特异性
This antibody detects endogenous levels of Human IL-17
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000;Flow Cyt 1:50-200; ELISA 1:5000-20000
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景（Background）
function:Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of the intracellular adhesion molecule-1 (ICAM-1) in fibroblasts.,online information:Interleukin-17 entry,PTM:Found both in glycosylated and nonglycosylated forms.,similarity:Belongs to the IL-17 family.,subunit:Homodimer.,tissue specificity:Restricted to activated memory T-cells.,
功能
regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, protein amino acid glycosylation, apoptosis, defense response, inflammatory response, immune response, cell-cell signaling,cell death, glycoprotein metabolic process, glycoprotein biosynthetic process, response to wounding, positive regulation of biosynthetic process, positive regulation of macromolecule biosynthetic process, positive regulation of macromolecule metabolic process, positive regulation of gene expression, programmed cell death, death, positive regulation of cellular biosynthetic process, biopolymer glycosylation, regulation of transcription, positive regulation of transcription, DNA-dependent, positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, positive regulation of transcription, positive regulation of transcription from RNA p
基因名称（Gene Name）
IL17A CTLA8 IL17
其他名称
Interleukin-17A (IL-17;IL-17A;Cytotoxic T-lymphocyte-associated antigen 8;CTLA-8)
Fields
>>Cytokine-cytokine receptor interaction;>>IL-17 signaling pathway;>>Th17 cell differentiation;>>Alcoholic liver disease;>>Inflammatory bowel disease;>>Rheumatoid arthritis
组织表达
Expressed in memory Th17 cells (at protein level).
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