免疫原
The antiserum was produced against synthesized peptide derived from human SLC30A9. AA range:181-230
特异性
ZnT-9 Polyclonal Antibody detects endogenous levels of ZnT-9 protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
function:Plays a role in the p160 coactivator signaling pathway that mediates transcriptional activation by nuclear receptors (By similarity). Plays a role in transcriptional activation of Wnt-responsive genes.,similarity:Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.,subunit:Interacts with GRIP1, ESR1 and AR.,tissue specificity:Ubiquitously expressed in fetal and adult tissues and cancer cell lines.,
功能
function:Plays a role in the p160 coactivator signaling pathway that mediates transcriptional activation by nuclear receptors (By similarity). Plays a role in transcriptional activation of Wnt-responsive genes.,similarity:Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.,subunit:Interacts with GRIP1, ESR1 and AR.,tissue specificity:Ubiquitously expressed in fetal and adult tissues and cancer cell lines.,
其他名称
SLC30A9; C4orf1; HUEL; Zinc transporter 9; ZnT-9; Human embryonic lung protein; HuEL; Solute carrier family 30 member 9
细胞定位
Membrane ; Multi-pass membrane protein . Nucleus . Cytoplasm . Cytoplasmic vesicle . Endoplasmic reticulum . Mainly in the cytoplasm (PubMed:10409434). Partial co-localization with endoplasmic reticulum (PubMed:28334855). .
组织表达
Ubiquitously expressed in fetal and adult tissues and cancer cell lines.