免疫原
The antiserum was produced against synthesized peptide derived from human MTIF3. AA range:69-118
特异性
IF3 Polyclonal Antibody detects endogenous levels of IF3 protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This gene encodes a translation initiation factor that is involved in mitochondrial protein synthesis. Polymorphism in this gene is associated with the onset of Parkinson's disease. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5. [provided by RefSeq, Oct 2009],
功能
function:IF-3 binds to the 28S ribosomal subunit and shifts the equilibrum between 55S ribosomes and their 39S and 28S subunits in favor of the free subunits, thus enhancing the availability of 28S subunits on which protein synthesis initiation begins.,similarity:Belongs to the IF-3 family.,
蛋白名称
Translation initiation factor IF-3 mitochondrial
其他名称
MTIF3; DC38; Translation initiation factor IF-3; mitochondrial; IF-3(Mt); IF-3Mt; IF3(mt); IF3mt
组织表达
Cervix,Colon,Dendritic cell,Melanocyte,