免疫原
The antiserum was produced against synthesized peptide derived from human FFAR3. AA range:11-60
特异性
GPR41 Polyclonal Antibody detects endogenous levels of GPR41 protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
function:Receptor for short chain fatty acids through a G(i)-protein-mediated inhibition of adenylyl cyclase and elevation of intracellular calcium. The rank order of potency for agonists of this receptor is propionate = pentanoate = butyrate > acetate > formate.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Highest level in adipose tissue, and lower expression across all tissues tested.,
功能
function:Receptor for short chain fatty acids through a G(i)-protein-mediated inhibition of adenylyl cyclase and elevation of intracellular calcium. The rank order of potency for agonists of this receptor is propionate = pentanoate = butyrate > acetate > formate.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Highest level in adipose tissue, and lower expression across all tissues tested.,
蛋白名称
Free fatty acid receptor 3
其他名称
FFAR3; GPR41; Free fatty acid receptor 3; G-protein coupled receptor 41
细胞定位
Cell membrane ; Multi-pass membrane protein .
组织表达
Highest level in adipose tissue, and lower expression across all tissues tested. Expressed in sympathetic ganglia.