免疫原
The antiserum was produced against synthesized peptide derived from human LIPC. AA range:301-350
特异性
Hepatic Lipase Polyclonal Antibody detects endogenous levels of Hepatic Lipase protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
LIPC encodes hepatic triglyceride lipase, which is expressed in liver. LIPC has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. [provided by RefSeq, Jul 2008],
功能
catalytic activity:Triacylglycerol + H(2)O = diacylglycerol + a carboxylate.,disease:Defects in LIPC are the cause of hepatic lipase deficiency (HL deficiency) [MIM:151670].,function:Hepatic lipase has the capacity to catalyze hydrolysis of phospholipids, mono-, di-, and triglycerides, and acyl-CoA thioesters. It is an important enzyme in HDL metabolism. Hepatic lipase binds heparin.,online information:The Singapore human mutation and polymorphism database,similarity:Belongs to the AB hydrolase superfamily. Lipase family.,similarity:Contains 1 PLAT domain.,
蛋白名称
Hepatic triacylglycerol lipase
其他名称
LIPC; HTGL; Hepatic triacylglycerol lipase; HL; Hepatic lipase; Lipase member C
Fields
>>Glycerolipid metabolism;>>Metabolic pathways;>>Cholesterol metabolism
组织表达
Donated clones,Liver,Thymus,
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