免疫原
Synthesized peptide derived from human WAPL; WAPAL
特异性
This antibody detects endogenous levels of WAPL; WAPAL at Human, Mouse
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Regulator of sister chromatid cohesion in mitosis which negatively regulates cohesin association with chromatin. Involved in both sister chromatid cohesion during interphase and sister-chromatid resolution during early stages of mitosis. Couples DNA replication to sister chromatid cohesion. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair.
基因名称（Gene Name）
WAPAL FOE KIAA0261 WAPL
蛋白名称
Wings apart-like protein homolog (Friend of EBNA2 protein)
细胞定位
[Isoform 2]: Nucleus.; Nucleus. Chromosome. Cytoplasm. Associates with chromatin through the cohesin complex during interphase. Released in the cytoplasm from nuclear envelope breakdown until anaphase, it reaccumulates in nucleus at telophase.
组织表达
Isoform 1 is highly expressed in uterine cervix tumor. Isoform 2 is widely expressed with a high level in skeletal muscle and heart.
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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