免疫原
Synthesized peptide derived from human protein . at AA range: 140-220
特异性
BKRB2 Monoclonal Antibody detects endogenous levels of protein.
组成（Formulation）
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene encodes a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. This receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. Alternate start codons result in two isoforms of the protein. [provided by RefSeq, Jul 2008],
功能
function:Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.,online information:Bradykinin receptor entry,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Ubiquitous. Widespread in normal smooth muscle tissue and neurons.,
基因名称（Gene Name）
BDKRB2 BKR2
蛋白名称
B2 bradykinin receptor (B2R) (BK-2 receptor)
Fields
>>Calcium signaling pathway;>>cGMP-PKG signaling pathway;>>Sphingolipid signaling pathway;>>Neuroactive ligand-receptor interaction;>>Complement and coagulation cascades;>>Inflammatory mediator regulation of TRP channels;>>Regulation of actin cytoskeleton;>>Endocrine and other factor-regulated calcium reabsorption;>>Chagas disease;>>Pathways in cancer
细胞定位
Cell membrane; Multi-pass membrane protein.
组织表达
Ubiquitous. Widespread in normal smooth muscle tissue and neurons.
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