免疫原
The antiserum was produced against synthesized peptide derived from human NRBF2. AA range:140-189
特异性
NRBF-2 Monoclonal Antibody detects endogenous levels of NRBF-2 protein.
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
function:May modulate transcriptional activation by target nuclear receptors. Can act as transcriptional activator (in vitro).,subunit:Interacts with PPARA, PPARD and PPARG. Interacts with RARA, RARG and RXRA in the presence of bound ligand.,tissue specificity:Detected in keratinocytes, liver and placenta.,
功能
function:May modulate transcriptional activation by target nuclear receptors. Can act as transcriptional activator (in vitro).,subunit:Interacts with PPARA, PPARD and PPARG. Interacts with RARA, RARG and RXRA in the presence of bound ligand.,tissue specificity:Detected in keratinocytes, liver and placenta.,
蛋白名称
Nuclear receptor-binding factor 2
其他名称
NRBF2; COPR; Nuclear receptor-binding factor 2; NRBF-2; Comodulator of PPAR and RXR
Fields
>>Autophagy - animal;>>Alzheimer disease;>>Amyotrophic lateral sclerosis;>>Huntington disease;>>Spinocerebellar ataxia;>>Pathways of neurodegeneration - multiple diseases
细胞定位
Nucleus . Cytoplasm . Cytoplasmic vesicle . Cytoplasmic vesicle, autophagosome .
组织表达
Detected in keratinocytes, liver and placenta (PubMed:15610520). Expressed in a subset of cells in pediatric medulloblastoma (PubMed:18619852).
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