免疫原
Synthesized peptide derived from human C-ternal S43A3
特异性
This antibody detects endogenous levels of S43A3 at Human, Mouse
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 IHC 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
Sodium-independent purine-selective nucleobase transporter which mediates the equilibrative transport of extracellular purine nucleobases such as adenine, guanine and hypoxanthine . May regulate fatty acid (FA) transport in adipocytes, acting as a positive regulator of FA efflux and as a negative regulator of FA uptake (By similarity). ; [Isoform 1]: Sodium-independent purine-selective nucleobase transporter which mediates the equilibrative transport of extracellular purine nucleobase adenine . Mediates the influx and efflux of the purine nucleobase analog drug 6-mercaptopurine across the membrane . ; [Isoform 2]: Sodium-independent purine-selective nucleobase transporter which mediates the equilibrative transport of extracellular purine nucleobase adenine . Mediates the influx and efflux of the purine nucleobase analog drug 6-mercaptopurine across the membrane .
基因名称(Gene Name)
SLC43A3 PSEC0252
蛋白名称
Solute carrier family 43 member 3 (Protein FOAP-13)
其他名称
Solute carrier family 43 member 3 (Protein FOAP-13)
细胞定位
Basolateral cell membrane ; Multi-pass membrane protein .
组织表达
Widely expressed with highest levels in the liver and lung, followed by the pancreas (PubMed:26455426). Highly expressed in macrophages (Ref.1).