免疫原
Synthesized peptide derived from human WIPF3 AA range: 66-116
特异性
This antibody detects endogenous levels of WIPF3 at Human/Mouse/Rat
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
domain:The KLKR motif is essential for G-actin binding and for actin polymerization.,domain:The profilin-binding motif has been implicated in the interaction with profilin and SH3 domains.,domain:The WH2 domain is found in a number of putative actin-binding proteins.,function:May be a regulator of cytoskeletal organization. May have a role in spermatogenesis.,similarity:Belongs to the verprolin family.,similarity:Contains 1 WH2 domain.,subcellular location:In hippocampal neurons colocalizes with WASL in the cell body, axons and the growth cone.,subunit:Interacts with WASL, and monomeric and filamentous actin.,
基因名称(Gene Name)
WIPF3 CR16
Fields
>>Endocytosis;>>Pathogenic Escherichia coli infection;>>Yersinia infection
细胞定位
Cytoplasm. In hippocampal neurons colocalizes with WASL in the cell body, axons and the growth cone. .