免疫原
The antiserum was produced against synthesized peptide derived from human Collagen XXIII alpha1. AA range:461-510
特异性
COL23A1 Polyclonal Antibody detects endogenous levels of COL23A1 protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
COL23A1 is a member of the transmembrane collagens, a subfamily of the nonfibrillar collagens that contain a single pass hydrophobic transmembrane domain (Banyard et al., 2003 [PubMed 12644459]).[supplied by OMIM, Mar 2008],
功能
PTM:Undergoes proteolytic cleavage by furin protease to yield a 60 kDa soluble form that forms an homotrimer and exhibits a low affinity interaction with heparin.,similarity:Contains 5 collagen-like domains.,subunit:Homotrimer.,
蛋白名称
Collagen alpha-1(XXIII) chain
其他名称
COL23A1; Collagen alpha-1(XXIII) chain
Fields
>>Protein digestion and absorption
细胞定位
Cell membrane ; Single-pass type II membrane protein ; Extracellular side .
组织表达
Brain,Placenta,Testis,