免疫原
The antiserum was produced against synthesized peptide derived from human CLCC1. AA range:391-440
特异性
CLCC1 Polyclonal Antibody detects endogenous levels of CLCC1 protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
function:Seems to act as a chloride ion channel.,similarity:Belongs to the chloride channel MCLC family.,
功能
function:Seems to act as a chloride ion channel.,similarity:Belongs to the chloride channel MCLC family.,
蛋白名称
Chloride channel CLIC-like protein 1
其他名称
CLCC1; KIAA0761; MCLC; Chloride channel CLIC-like protein 1; Mid-1-related chloride channel protein 1
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein . Golgi apparatus membrane ; Multi-pass membrane protein . Nucleus membrane ; Multi-pass membrane protein . Within the endoplasmic reticulum (ER), localizes to the mitochondria-associated ER membrane, a zone of contact between the ER and mitochondrial membranes. .
组织表达
Expressed in the retina of the eye, with extensive expression in the lamina cribrosa, optic nerve, ganglion cell layer, inner nuclear layer, outer nuclear layer and retinal pigment epithelium.