免疫原
The antiserum was produced against synthesized peptide derived from human BNIP2. AA range:265-314
特异性
BNIP-2 Polyclonal Antibody detects endogenous levels of BNIP-2 protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/40000. Not yet tested in other applications.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],
功能
function:Implicated in the suppression of cell death. Interacts with the BCL-2 and adenovirus E1B 19 kDa proteins.,similarity:Contains 1 CRAL-TRIO domain.,subcellular location:Localizes to the nuclear envelope region and to other cytoplasmic structures.,
蛋白名称
BCL2/adenovirus E1B 19 kDa protein-interacting protein 2
其他名称
BNIP2; NIP2; BCL2/adenovirus E1B 19 kDa protein-interacting protein 2
细胞定位
Cytoplasm. Cytoplasm, perinuclear region. Localizes to the nuclear envelope region and to other cytoplasmic structures.