免疫原
Synthesized peptide derived from Rab 26 . at AA range: 180-256
特异性
Rab 26 Polyclonal Antibody detects endogenous levels of Rab 26 protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/40000.. IF 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
Members of the RAB protein family, including RAB26, are important regulators of vesicular fusion and trafficking. The RAB family of small G proteins regulates intercellular vesicle trafficking, including exocytosis, endocytosis, and recycling (summary by Seki et al., 2000 [PubMed 11043516]).[supplied by OMIM, Nov 2010],
功能
function:Participates in exocrine secretion: regulates the secretion of acinar granules in the parotid gland.,similarity:Belongs to the small GTPase superfamily. Rab family.,tissue specificity:Predominantly expressed in brain.,
蛋白名称
Ras-related protein Rab-26
其他名称
RAB26; Ras-related protein Rab-26
细胞定位
Golgi apparatus membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasmic vesicle, secretory vesicle membrane ; Lipid-anchor ; Cytoplasmic side . Not localized at the plasma membrane (By similarity). Inhibition of S-geranylgeranyl cysteine formation abolishes membrane location. .
组织表达
Predominantly expressed in brain.