免疫原
The antiserum was produced against synthesized peptide derived from human RAP2C. AA range:97-146
特异性
Rap 2C Polyclonal Antibody detects endogenous levels of Rap 2C protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000;IHC-p 1:50-300
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
The protein encoded by this gene is a member of the Ras-related protein subfamily of the Ras GTPase superfamily. Members of this family are small GTPases that act as molecular switches to regulate cellular proliferation, differentiation, and apoptosis. This protein has been reported to activate in vitro transcriptional activity of the serum response element. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012],
功能
similarity:Belongs to the small GTPase superfamily. Ras family.,tissue specificity:Expressed in mononuclear leukocytes and megakaryocytes. Not detected in platelets.,
蛋白名称
Ras-related protein Rap-2c
其他名称
RAP2C; Ras-related protein Rap-2c
细胞定位
Cytoplasm . Recycling endosome membrane ; Lipid-anchor ; Cytoplasmic side .
组织表达
Expressed in liver, skeletal muscle, prostate, uterus, rectum, stomach, and bladder and to a lower extent in brain, kidney, pancreas, and bone marrow. Expressed in mononuclear leukocytes and megakaryocytes.