免疫原
Synthesized peptide derived from Rab 31 . at AA range: 50-130
特异性
Rab 31 Polyclonal Antibody detects endogenous levels of Rab 31 protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
Small GTP-binding proteins of the RAB family, such as RAB31, play essential roles in vesicle and granule targeting (Bao et al., 2002 [PubMed 11784320]).[supplied by OMIM, Jul 2009],
功能
similarity:Belongs to the small GTPase superfamily. Rab family.,tissue specificity:Highest expression in placenta and brain with lower levels in heart and lung. Not detected in liver, skeletal muscle, kidney or pancreas.,
蛋白名称
Ras-related protein Rab-31
其他名称
RAB31; RAB22B; Ras-related protein Rab-31; Ras-related protein Rab-22B
细胞定位
Golgi apparatus, trans-Golgi network . Golgi apparatus, trans-Golgi network membrane ; Lipid-anchor ; Cytoplasmic side . Early endosome . Cytoplasmic vesicle, phagosome . Cytoplasmic vesicle, phagosome membrane ; Lipid-anchor ; Cytoplasmic side . Rapidly recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211). .
组织表达
Highest expression in placenta and brain with lower levels in heart and lung. Not detected in liver, skeletal muscle, kidney or pancreas.