免疫原
The antiserum was produced against synthesized peptide derived from human GUF1. AA range:421-470
特异性
GUF1 Polyclonal Antibody detects endogenous levels of GUF1 protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene encodes a GTPase that triggers back-translocation of the elongating ribosome during mitochondrial protein synthesis. The protein contains a highly conserved C-terminal domain not found in other GTPases that facilitates tRNA binding. The encoded protein is thought to prevent misincorporation of amino acids in stressful, suboptimal conditions. An allelic variant in this gene has been associated with early infantile epileptic encephalopathy-40. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016],
功能
similarity:Belongs to the GTP-binding elongation factor family. LepA subfamily.,
蛋白名称
Translation factor GUF1 mitochondrial
其他名称
GUF1; Translation factor GUF1; mitochondrial; Elongation factor 4 homolog; EF-4; GTPase GUF1; Ribosomal back-translocase
细胞定位
Mitochondrion inner membrane ; Peripheral membrane protein ; Matrix side .
组织表达
Brain,Colon,Lung adenocarcinoma,Teratocarcinoma,
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