免疫原
The antiserum was produced against synthesized peptide derived from human HIBADH. AA range:281-330
特异性
HIBADH Polyclonal Antibody detects endogenous levels of HIBADH protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This gene encodes a mitochondrial 3-hydroxyisobutyrate dehydrogenase enzyme. The encoded protein plays a critical role in the catabolism of L-valine by catalyzing the oxidation of 3-hydroxyisobutyrate to methylmalonate semialdehyde. [provided by RefSeq, Nov 2011],
功能
catalytic activity:3-hydroxy-2-methylpropanoate + NAD(+) = 2-methyl-3-oxopropanoate + NADH.,similarity:Belongs to the 3-hydroxyisobutyrate dehydrogenase family.,subunit:Homodimer.,
蛋白名称
3-hydroxyisobutyrate dehydrogenase mitochondrial
其他名称
HIBADH; 3-hydroxyisobutyrate dehydrogenase; mitochondrial; HIBADH
Fields
>>Valine, leucine and isoleucine degradation;>>Metabolic pathways
组织表达
Detected in skin fibroblasts.