免疫原
The antiserum was produced against synthesized peptide derived from human RCBTB1. AA range:251-300
特异性
CLLD7 Polyclonal Antibody detects endogenous levels of CLLD7 protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene encodes a protein with an N-terminal RCC1 domain and a C-terminal BTB (broad complex, tramtrack and bric-a-brac) domain. In rat, over-expression of this gene in vascular smooth muscle cells induced cellular hypertrophy. In rat, the C-terminus of RCBTB1 interacts with the angiotensin II receptor-1A. In humans, this gene maps to a region of chromosome 13q that is frequently deleted in B-cell chronic lymphocytic leukemia and other lymphoid malignancies. [provided by RefSeq, Jul 2008],
功能
function:May be involved in cell cycle regulation by chromatin remodeling.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 2 BTB (POZ) domains.,similarity:Contains 6 RCC1 repeats.,tissue specificity:Ubiquitously expressed.,
蛋白名称
RCC1 and BTB domain-containing protein 1
其他名称
RCBTB1; CLLD7; E4.5; RCC1 and BTB domain-containing protein 1; Chronic lymphocytic leukemia deletion region gene 7 protein; CLL deletion region gene 7 protein; Regulator of chromosome condensation and BTB domain-containing protein 1
组织表达
Ubiquitously expressed (PubMed:11306461, PubMed:27486781). In the retina, present in the nerve fiber layer and to a lesser extent in the inner and outer plexiform layers (at protein level) (PubMed:27486781).
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