免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human CCL26. AA range:31-80
特异性
Eotaxin-3 Polyclonal Antibody detects endogenous levels of Eotaxin-3 protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000.. IF 1:50-200
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene is one of two Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 7. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for normal peripheral blood eosinophils and basophils. The product of this gene is one of three related chemokines that specifically activate chemokine receptor CCR3. This chemokine may contribute to the eosinophil accumulation in atopic diseases. [provided by RefSeq, Jul 2008],
功能
function:Chemotactic for eosinophils and basophils. Binds to CCR3.,online information:CCL26 entry,similarity:Belongs to the intercrine beta (chemokine CC) family.,subunit:Monomer.,tissue specificity:Ubiquitously expressed at low levels in various tissues including heart and ovary.,
蛋白名称
C-C motif chemokine 26
其他名称
CCL26; SCYA26; C-C motif chemokine 26; CC chemokine IMAC; Eotaxin-3; Macrophage inflammatory protein 4-alpha; MIP-4-alpha; Small-inducible cytokine A26; Thymic stroma chemokine-1; TSC-1
Fields
>>Cytokine-cytokine receptor interaction;>>Viral protein interaction with cytokine and cytokine receptor;>>Chemokine signaling pathway
组织表达
Ubiquitously expressed at low levels in various tissues including heart and ovary.
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