免疫原
The antiserum was produced against synthesized peptide derived from the N-terminal region of human SCG3. AA range:21-70
特异性
Sg III Polyclonal Antibody detects endogenous levels of Sg III protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000.. IF 1:50-200
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
secretogranin III(SCG3) Homo sapiens The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Granins may serve as precursors for biologically active peptides. Some granins have been shown to function as helper proteins in sorting and proteolytic processing of prohormones; however, the function of this protein is unknown. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009],
功能
subcellular location:Neuroendocrine and endocrine secretory granules.,tissue specificity:Expressed in brain, heart, kidney, liver and skeletal muscle.,
其他名称
SCG3; Secretogranin-3; Secretogranin III; SgIII
细胞定位
Cytoplasmic vesicle, secretory vesicle . Cytoplasmic vesicle, secretory vesicle membrane ; Peripheral membrane protein . Secreted . Associated with the secretory granule membrane through direct binding to cholesterol-enriched lipid rafts. .
组织表达
Expressed in brain, heart, kidney, liver and skeletal muscle.
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