免疫原
Synthesized peptide derived from PIG-F . at AA range: 130-210
特异性
PIG-F Polyclonal Antibody detects endogenous levels of PIG-F protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This gene encodes a protein involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor, a glycolipid containing three mannose molecules in its core backbone, is found on many blood cells where it serves to anchor proteins to the cell surface. The encoded protein and another GPI synthesis protein, PIGO, function in the transfer of ethanolaminephosphate to the third mannose in GPI. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008],
功能
function:Involved in GPI-anchor biosynthesis through the transfer of ethanolamine phosphate to the third mannose of GPI.,pathway:Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.,similarity:Belongs to the PIGF family.,subunit:Forms a complex with PIGG and PIGO. PIGF is required to stabilize PIGG and PIGO.,
蛋白名称
Phosphatidylinositol-glycan biosynthesis class F protein
其他名称
PIGF; Phosphatidylinositol-glycan biosynthesis class F protein; PIG-F; GPI11 homolog
Fields
>>Glycosylphosphatidylinositol (GPI)-anchor biosynthesis;>>Metabolic pathways
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein .