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Pax-4 Monoclonal Antibody

说明书

BYab-15737

  • 20UL ¥460 50UL ¥945 100UL ¥1350
  • 货期: 3天左右

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产品简介>

宿主
反应性
应用
WB;ELISA
分子量(DA)
免疫原
Purified recombinant fragment of human Pax-4 expressed in E. Coli.
特异性
Pax-4 Monoclonal Antibody detects endogenous levels of Pax-4 protein.
来源
Monoclonal, Mouse
组成(Formulation)
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
稀释比例
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
纯化工艺(Immunogen)
Affinity purification
浓度
背景(Background)
This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The paired box 4 gene is involved in pancreatic islet development and mouse studies have demonstrated a role for this gene in differentiation of insulin-producing beta cells. [provided by RefSeq, Jul 2008],
功能
disease:Defects in PAX4 are a cause of noninsulin-dependent diabetes mellitus (NIDDM) [MIM:125853]; also known as diabetes mellitus type 2 or maturity-onset diabetes. NIDDM is characterized by an autosomal dominant mode of inheritance, onset during adulthood and insulin resistance.,disease:Defects in PAX4 are the cause of maturity-onset diabetes of the young type 9 (MODY9) [MIM:612225]. MODY [MIM:606391] is a form of diabetes mellitus characterized by an autosomal dominant mode of inheritance, age of onset of 25 years or younger and a primary defect in insulin secretion.,disease:Genetic variations in PAX4 are associated with susceptibility to insulin-dependent diabetes mellitus (IDDM) [MIM:222100]. IDDM normally starts in childhood or adolescence and is caused by the body's own immune system which destroys the insulin-producing beta cells in the pancreas. Classical features are polydipsi
基因名称(Gene Name)
PAX4
蛋白名称
Paired box protein Pax-4
简称
Pax-4
其他名称
PAX4; Paired box protein Pax-4
Fields
>>Maturity onset diabetes of the young
人基因ID
5078
人蛋白质序列数据库
O43316
小鼠基因ID
小鼠蛋白质序列数据库
P32115
大鼠基因ID
大鼠蛋白质序列数据库
细胞定位
Nucleus.
组织表达
Colon,Insulinoma,PCR rescued clones,Placenta,
储存(Storage)
-20°C/1 year

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Pax-4 Monoclonal Antibody

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