免疫原
Synthesized peptide derived from human S100P
特异性
The antibody can specifically recognize human S100P protein.
来源
Mouse, Monoclonal/IgG1, Kappa
组成(Formulation)
PBS, pH7.2, 0.03% Porcolin 300, containing stabilizing protein
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
背景(Background)
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 4p16. This protein, in addition to binding Ca2+, also binds Zn2+ and Mg2+. This protein may play a role in the etiology of prostate cancer. [provided by RefSeq, Jul 2008],
功能
miscellaneous:This protein binds two calcium ions.,similarity:Belongs to the S-100 family.,similarity:Contains 2 EF-hand domains.,subcellular location:Colocalizes with S100PBP in the nucleus.,subunit:Homodimer. Interacts with S100PBP and S100Z.,tissue specificity:Up-regulated in various pancreatic ductal adenocarcinomas and pancreatic intraepithelial neoplasias.,
基因名称(Gene Name)
S100P S100E
蛋白名称
MIG9;Migration inducing gene 9;Protein S100-E;Protein S100-P;Protein S100P;S100 calcium binding protein P;S100 calcium-binding protein P;S100 P;S100E;S100P;S100P_HUMAN
其他名称
MIG9;Migration inducing gene 9;Protein S100-E;Protein S100-P;Protein S100P;S100 calcium binding protein P;S100 calcium-binding protein P;S100 P;S100E;S100P;S100P_HUMAN
细胞定位
Nuclear, Cytoplasmic