免疫原
Synthesized peptide derived from human Prostatic Acid Phosphatase(PSAP)
特异性
This antibody detects endogenous levels of Prostatic Acid Phosphatase(PSAP) at Human
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC-p 1:200. IF 1:50-200
纯化工艺（Immunogen）
The antibody was affinity-purified from Cell supernatant by affinity-chromatography using specific immunogen.
功能
catalytic activity:A phosphate monoester + H(2)O = an alcohol + phosphate.,similarity:Belongs to the histidine acid phosphatase family.,subcellular location:Predominantly localized in the plasma membrane but also detected in intracellular vesicles.,subunit:Homodimer.,
蛋白名称
Prostatic Acid Phosphatase(PSAP)
其他名称
Prostatic acid phosphatase (PAP;EC 3.1.3.2;5'-nucleotidase;5'-NT;EC 3.1.3.5;Ecto-5'-nucleotidase;Thiamine monophosphatase;TMPase) [Cleaved into: PAPf39]
细胞定位
[Isoform 1]: Secreted .; [Isoform 2]: Cell membrane ; Single-pass type I membrane protein . Lysosome membrane ; Single-pass type I membrane protein . Nucleus . Cytoplasm, cytosol . Appears to shuttle between the cell membrane and intracellular vesicles. Colocalizes with FLOT1 at cell membrane and in intracellular vesicles (PubMed:17638863). Colocalizes with LAMP2 on the lysosome membrane (PubMed:17897319). .
组织表达
Highly expressed in the prostate, restricted to glandular and ductal epithelial cells. Also expressed in bladder, kidney, pancreas, lung, cervix, testis and ovary. Weak expression in a subset of pancreatic islet cells, squamous epithelia, the pilosebaceous unit, colonic neuroendocrine cells and skin adnexal structures. Low expression in prostate carcinoma cells and tissues. ; [Isoform 2]: Widely expressed. Expressed in the sarcolemma of skeletal muscle.
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