免疫原
The antiserum was produced against synthesized peptide derived from human BLCAP. AA range:38-87
特异性
Bc10 Polyclonal Antibody detects endogenous levels of Bc10 protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000 Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene encodes a protein that reduces cell growth by stimulating apoptosis. Alternative splicing and the use of alternative promoters result in multiple transcript variants encoding the same protein. This gene is imprinted in brain where different transcript variants are expressed from each parental allele. Transcript variants initiating from the upstream promoter are expressed preferentially from the maternal allele, while transcript variants initiating downstream of the interspersed NNAT gene (GeneID:4826) are expressed from the paternal allele. Transcripts at this locus may also undergo A to I editing, resulting in amino acid changes at three positions in the N-terminus of the protein. [provided by RefSeq, Nov 2015],
功能
similarity:Belongs to the BLCAP family.,tissue specificity:Expressed in cervical tissues. Down-regulated during bladder cancer progression and in most cervical carcinomas.,
蛋白名称
Bladder cancer-associated protein
其他名称
BLCAP; BC10; Bladder cancer-associated protein; Bladder cancer 10 kDa protein; Bc10
细胞定位
Membrane ; Multi-pass membrane protein .
组织表达
Ubiquitous. Expressed in cervical tissues. Down-regulated in bladder invasive carcinoma, renal cell carcinoma and in primary cervical carcinoma.
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