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Mart-1/Melan-A mouse mAb(ABT-Mart1)

说明书

BYab-15463

  • 20UL ¥460 50UL ¥945 100UL ¥1350
  • 货期: 3天左右

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宿主
反应性
应用
IHC;IF
分子量(DA)
免疫原
Synthesized peptide derived from human Mart-1/Melan-A
特异性
This antibody detects endogenous levels of human Mart-1/Melan-A. Heat-induced epitope retrieval (HIER) TRIS-EDTA of pH9.0 was highly recommended as antigen repair method in paraffin section
来源
Mouse, Monoclonal/IgG2b, Kappa
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC-p 1:300-500. IF 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
浓度
背景(Background)
tissue specificity:Expression is restricted to melanoma and melanocyte cell lines and retina.,
功能
tissue specificity:Expression is restricted to melanoma and melanocyte cell lines and retina.,
基因名称(Gene Name)
MLANA MART1
蛋白名称
Mart-1/Melan-A
简称
Melan-A
其他名称
Melanoma antigen recognized by T-cells 1 (MART-1;Antigen LB39-AA;Antigen SK29-AA;Protein Melan-A)
Fields
人基因ID
2315
人蛋白质序列数据库
Q16655
小鼠基因ID
小鼠蛋白质序列数据库
大鼠基因ID
大鼠蛋白质序列数据库
细胞定位
Endoplasmic reticulum membrane; Single-pass type III membrane protein. Golgi apparatus. Golgi apparatus, trans-Golgi network membrane. Melanosome. Also found in small vesicles and tubules dispersed over the entire cytoplasm. A small fraction of the protein is inserted into the membrane in an inverted orientation. Inversion of membrane topology results in the relocalization of the protein from a predominant Golgi/post-Golgi area to the endoplasmic reticulum. Melanoma cells expressing the protein with an inverted membrane topology are more effectively recognized by specific cytolytic T-lymphocytes than those expressing the protein in its native membrane orientation.
组织表达
Expression is restricted to melanoma and melanocyte cell lines and retina.
储存(Storage)
-20°C/1 year

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Mart-1/Melan-A mouse mAb(ABT-Mart1)

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