免疫原
The antiserum was produced against synthesized peptide derived from human CKI-alpha1/L. AA range:141-190
特异性
Casein Kinase I α1/1L Polyclonal Antibody detects endogenous levels of Casein Kinase I α1/1L protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000 Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling.,similarity:Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.,similarity:Contains 1 protein kinase domain.,
功能
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling.,similarity:Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.,similarity:Contains 1 protein kinase domain.,
基因名称（Gene Name）
CSNK1A1/CSNK1A1L
蛋白名称
Casein kinase I isoform alpha/Casein kinase I isoform alpha-like
其他名称
CSNK1A1L; Casein kinase I isoform alpha-like; CKI-alpha-like; CK1; CSNK1A1; Casein kinase I isoform alpha; CKI-alpha; CK1
Fields
>>Wnt signaling pathway;>>Hedgehog signaling pathway;>>Alzheimer disease;>>Pathways of neurodegeneration - multiple diseases;>>Human papillomavirus infection;>>Breast cancer;>>Hepatocellular carcinoma;>>Gastric cancer
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