免疫原
The antiserum was produced against synthesized peptide derived from human SCTR. AA range:100-149
特异性
Secretin Receptor Polyclonal Antibody detects endogenous levels of Secretin Receptor protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
secretin receptor(SCTR) Homo sapiens The protein encoded by this gene is a G protein-coupled receptor and belongs to the glucagon-VIP-secretin receptor family. It binds secretin which is the most potent regulator of pancreatic bicarbonate, electrolyte and volume secretion. Secretin and its receptor are suggested to be involved in pancreatic cancer and autism. [provided by RefSeq, Jul 2008],
功能
function:This is a receptor for secretin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.,similarity:Belongs to the G-protein coupled receptor 2 family.,
其他名称
SCTR; Secretin receptor; SCT-R
Fields
>>Neuroactive ligand-receptor interaction;>>Pancreatic secretion;>>Bile secretion
细胞定位
Cell membrane ; Multi-pass membrane protein .
组织表达
Brain,Kidney,Lung,Pancreas,
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