免疫原
The antiserum was produced against synthesized peptide derived from human OR8G5. AA range:197-246
特异性
Olfactory receptor 8G5 Polyclonal Antibody detects endogenous levels of Olfactory receptor 8G5 protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
olfactory receptor family 8 subfamily G member 5(OR8G5) Homo sapiens Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008],
功能
function:Odorant receptor .,polymorphism:A stop codon in the gene coding for this protein at position Tyr-259 is responsible for functional diversity thus producing thus a pseudogene.,similarity:Belongs to the G-protein coupled receptor 1 family.,
蛋白名称
Olfactory receptor 8G5
简称
Olfactory receptor 8G5
其他名称
OR8G5; OR8G5P; OR8G6; Olfactory receptor 8G5; Olfactory receptor 8G6; Olfactory receptor OR11-298
Fields
>>Olfactory transduction
细胞定位
Cell membrane; Multi-pass membrane protein.